Labs on a Chip: Meet the Stripped Down Rat
by Roxanne Khamsi
Nature, 5 May 2005
For Michael Shuler, downsizing is not a dirty word. In the mid-1990s, his lab bench was cluttered with flasks connected by surgical tubing. Each flask contained cells from a different organ, suspended in nourishing fluids. Shuler's goal was to model how chemicals entering the body can be metabolized into more toxic forms. Today, the apparatus has been shrunk to a tiny device that looks like something from the insides of your mobile phone.
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